Concept:DNA packaging involves winding DNA around histone proteins to form nucleosomes and further compacting chromatin.
Key Fact:Histones are positively charged basic proteins rich in lysine and arginine; DNA is negatively charged.
Explanation:Statement A: Eight histone molecules (two each of H2A, H2B, H3, H4) form a histone octamer — correct.
Statement B: Histones are positively charged due to basic amino acids, not negatively charged — incorrect.
Statement C: Histones are rich in basic amino acids lysine and arginine — correct.
Statement D: DNA is negatively charged, not positively charged; it is wrapped around the positively charged histone octamer — incorrect.
Statement E: Higher-order chromatin packaging requires non-histone chromosomal (NHC) proteins — correct.
Thus, correct statements are A, C, and E.
Answer:A. A, C and E only
