Concept:Use dzdy=dz/dxdy/dx to differentiate the given functions with respect to each other.Explanation:Let y=tan−1(x1+x2−1) and z=tan−1(1−x2x).Rationalise the expression inside y: x1+x2−1=1+x2+1x.Using the identity tan(2θ)=1+tan2θ+1tanθ, we get y=21tan−1x.Therefore, dxdy=2(1+x2)1.Now simplify z: tan−1(1−x2x)=sin−1x.So, dxdz=1−x21.Hence, dzdy=1−x212(1+x2)1=2(1+x2)1−x2.At x=21: dzdy=2(1+41)1−41=2523=53.Answer:53, which is Option C.