Synthetic : (of a substance) made by chemical synthesis, especially to imitate a natural product.Man-made : made or caused by human beings (as opposed to occurring or being made naturally).Natural : existing in or derived from nature; not made or caused by humankind.Exact : not approximated in any way; precise.Artifact : an object made by a human being, typically one of cultural or historical interest.Synonym of Artifact is Man-made